Highly Efficient Sex Chromosome Interchanges Produced By I-CreI Expression in Drosophila
نویسندگان
چکیده
منابع مشابه
Highly efficient sex chromosome interchanges produced by I-CreI expression in Drosophila.
The homing endonuclease I-CreI recognizes a site in the gene encoding the 23S rRNA of Chlamydomonas reinhardtii. A very similar sequence is present in the 28S rRNA genes that are located on the X and Y chromosomes of Drosophila melanogaster. In this work we show that I-CreI expression in Drosophila is capable of causing induced DNA damage and eliciting cell cycle arrest. Expression also caused ...
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ژورنال
عنوان ژورنال: Genetics
سال: 2005
ISSN: 1943-2631
DOI: 10.1534/genetics.104.040071